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Targeted Supplement Stack (Foundation Protocol)

biohacking · easy · 2 minutes daily (taking supplements)

What is Targeted Supplement Stack (Foundation Protocol)?

A synergistic daily supplement protocol targeting the most common modern deficiencies: magnesium, vitamin D3, vitamin K2, zinc, and omega-3. These work together — magnesium activates vitamin D, K2 directs calcium to bones, zinc supports immune and hormonal function.

Is there evidence for it?

EVIDENCEstrong

How do you do Targeted Supplement Stack (Foundation Protocol)?

  1. 1.Morning with breakfast (fat-containing meal): Vitamin D3 5,000 IU + Vitamin K2-MK7 200mcg (take together, both fat-soluble). Omega-3 fish oil 2,000-3,000mg total EPA+DHA. Zinc picolinate or glycinate 15-30mg.
  2. 2.Evening, 30-60 min before bed: Magnesium glycinate 300-400mg (promotes relaxation and sleep quality). Optionally add magnesium L-threonate 144mg elemental for cognitive support (crosses blood-brain barrier).
  3. 3.Consider splitting omega-3: 1,000mg with breakfast and 1,000mg with dinner for better absorption and sustained levels. Always take with fat-containing meals.
  4. 4.Get baseline blood work: test 25-OH vitamin D (target 40-60 ng/mL), RBC magnesium (target 5.2-6.5 mg/dL), serum zinc (target 80-120 mcg/dL), and omega-3 index (target 8-12%). Adjust doses based on labs.
  5. 5.Important interactions to avoid: don't take zinc and magnesium at the same time (they compete for absorption). Don't take calcium with zinc. Space iron supplements 2+ hours from zinc. Cycle zinc (5 days on, 2 days off) to avoid copper depletion.

How long does it take?

2 minutes daily (taking supplements).

Is it hard to start?

easy.

Source: Mito Health Magnesium Stacking Guide; iThrive Supplement Stack Guide; Cymbiotika; SingleCare Vitamin Interactions
supplements · magnesium · vitamin-d · vitamin-k2 · zinc · omega-3 · deficiency · foundation-protocol
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This is one entry from the library Shift matches against. It is general information, not advice about you, and nothing on this page came from anyone's conversation.