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Supplementation

5 techniques in Supplementation. Each one lists what it is, how to do it, how long it takes and what the evidence says.

Berberine (Metformin Alternative)
Berberine is a plant alkaloid that activates AMPK (the same pathway as metformin) and improves insulin sensitivity, blood sugar...
2 min/day (supplement with meals)
Collagen Supplementation Protocol
Hydrolyzed collagen peptides (2.5-15g/day) may improve skin elasticity, reduce wrinkles, support joint health, and one 2025 study...
2-5 min/day (mixing and consuming)
DHEA Supplementation for Aging
DHEA (dehydroepiandrosterone) is a hormone that peaks in your 20s and declines steadily with age. It's a precursor to both...
1 min/day (supplement) + biannual blood work
NMN/NR Supplementation (NAD+ Precursors)
David Sinclair's protocol centers on boosting NAD+ levels, which decline with age. NMN (nicotinamide mononucleotide) is the...
2 min/day (taking supplements)
Vitamin D Optimization
Consensus of 48 international vitamin D researchers recommends serum 25(OH)D levels of 40-60 ng/mL (100-150 nmol/L) for optimal...
1 min/day (supplement) + quarterly blood test
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